CME Grand Rounds Suzanne E. Lapi, PhD
Event Details
https://stanford.zoom.us/j/600003703?pwd=RjcwS2MvOG1qVkxyL3U0RmNtUDVWdz09 LKSC 120 and Via Zoom Meeting ID: 600 003 703Password: 566048Or iPhone one-tap (US
Event Details
https://stanford.zoom.us/j/600003703?pwd=RjcwS2MvOG1qVkxyL3U0RmNtUDVWdz09
LKSC 120 and Via Zoom
Meeting ID: 600 003 703
Password: 566048
Or iPhone one-tap (US Toll): +18333021536,,600003703# or +16507249799,,600003703#
Or Telephone:
Dial: +1 650 724 9799 (US, Canada, Caribbean Toll) or +1 833 302 1536 (US, Canada, Caribbean Toll Free)
International numbers available: https://stanford.zoom.us/u/acuqphnvqT
CME Grand Rounds – From Isotopes to Images: Applications of Radiometals for Nuclear Medicine
Suzanne E. Lapi, PhD
Professor of Radiology and Chemistry; Vice Chair of Research, Radiology; Director, UAB Cyclotron Facility, University of Alabama at Birmingham
ABSTRACT
Molecular imaging is a powerful technique that can be applied to basic, translational, and clinical research as well as to routine patient care. In particular, Positron Emission Tomography (PET) allows for spatial localization and quantification of biological processes such as metabolism, enzyme activity, cell proliferation, receptor density and cellular transport that are not readily assessed with conventional anatomic imaging techniques. Using the UAB TR24 cyclotron, our group has focused on the production and purification of radioactive isotopes to expand the toolbox of nuclear imaging agents. These have included transition metals such as 52Mn, 64Cu, 55Co, 89Zr, 43,47Sc and 45Ti. Additional research has developed chemistry to incorporate these radioisotopes into new imaging radiopharmaceuticals for preclinical or clinical research for many diseases. For example, our group has focused on the use of 89Zr radiolabeled antibodies for imaging of cell surface receptor expression (HER2, EGFR) in preclinical models and in a clinical trial of metastatic breast cancer patients. Additionally, we have been developing strategies for paired imaging and therapeutic agents.
Time
April 14, 2023 12:00 pm - 1:00 pm(GMT-07:00)
Location
LKSC LK120, Zoom
291 Campus Drive